Soft Tissues: Biaxial

The Challenge

Biaxial planar testing of soft tissues is often required to fully characterize the inherent anisotropic properties of the tissue or to set-up biaxial stress-strain states to provide more accurate in vivo simulation. With uniaxial testing, fibers may realign along the test axis, altering the mechanical properties of the tissue. In addition, constitutive models cannot be developed based on uniaxial testing alone.

The gripping technique must be capable of securely holding soft tissues, without causing damage, and lateral deformations must be unrestricted in order to ensure homogeneous specimen deformation in the gauge area under biaxial loading. In addition to this, strain measurement must not damage the tissue or cause stress concentrations and be able to account for strain in all directions of loading.

Our Solution

The Instron low-force planar-biaxial soft tissue system was developed to perform mechanical testing and property analysis of soft planar biomaterials, native tissues and tissue-engineered scaffolds.

The configurable system consists of four fatigue-rated actuators mounted to an air-suspended isolation table. The system is capable of running both uniaxial and biaxial tests to offer ultimate flexibility for soft tissue testing.

The FastTrack™ 8800 digital controller is capable of providing true planar-biaxial control, giving both translation and deformation control in both axes. This aids in the ability for highly accurate specimen center-point control, allowing the use of optical instruments mounted above the specimen. Such instrumentation includes non-contacting video extensometry for precise measurements of strain in two dimensions or microscope systems for structural observations. The exceptional resolution of the controller ensures accuracy when measuring the extremely low loads associated with many soft tissues.

A simple gripping method based on sutures and pulleys distributes the loading forces equally around the specimen, allowing simultaneous testing along the x and y axes. The entire system is easily configured with one of Instron's temperature-controlled environmental baths, for simulation of physiological conditions during testing.

Tissue sample with suture grips and unique non-contacting biaxial strain measurement system Planar-biaxial system for soft tissue testing
Tissue sample with suture grips and unique non-contacting biaxial strain measurement system
Tissue sample with suture grips and unique non-contacting biaxial strain measurement system
Planar-biaxial system for soft tissue testing
Planar-biaxial system for soft tissue testing

Other Biomaterials Applications

Soft Tissues: Planar-biaxial System
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